Uploaded image for project: 'IGB'
  1. IGB
  2. IGBF-4299

Hunting for read depth in M6A sites of interest

    Details

    • Type: Task
    • Status: Closed (View Workflow)
    • Priority: Major
    • Resolution: Done
    • Affects Version/s: None
    • Fix Version/s: None
    • Labels:
      None

      Description

      GOAL: To look at how many reads align in 3' UTR regions of interest mentioned by Kausik.

      Rob's prevailing thought: No reads align to these areas. Prove him wrong.

      1. Get file from Kausik's email with the gene of interest
      2. Find relevant reference annotation (GFF, GTF, refflat file, bed) that contains the gene name.
      3. Within this file, identify the coordinates for the 3'UTR
      4. Get coordinates for m6A sites related to this gene.
      5. Check how many reads for these sites and for the 3' UTR in general.
      6. Repeat for each gene.
      7. Repeat for each of the 10 files (Ring, troph, Schitz, etc)

      To figure out how to get the depth of reads using samtools.
      Can it all be done in Python but we use the samtools.

        Attachments

          Activity

          robofjoy Robert Reid created issue -
          robofjoy Robert Reid made changes -
          Field Original Value New Value
          Epic Link IGBF-2993 [ 21429 ]
          robofjoy Robert Reid made changes -
          Status To-Do [ 10305 ] In Progress [ 3 ]
          bbendick Brandon Bendickson made changes -
          Status In Progress [ 3 ] To-Do [ 10305 ]
          ann.loraine Ann Loraine made changes -
          Sprint Fall 1 [ 83 ] Fall 1, Fall 2 [ 83, 225 ]
          ann.loraine Ann Loraine made changes -
          Rank Ranked higher
          bbendick Brandon Bendickson made changes -
          Status To-Do [ 10305 ] In Progress [ 3 ]
          bbendick Brandon Bendickson made changes -
          Status In Progress [ 3 ] Needs 1st Level Review [ 10005 ]
          bbendick Brandon Bendickson made changes -
          Assignee Brandon Bendickson [ bbendick ] Robert Reid [ robertreid ]
          bbendick Brandon Bendickson made changes -
          Status Needs 1st Level Review [ 10005 ] First Level Review in Progress [ 10301 ]
          bbendick Brandon Bendickson made changes -
          Status First Level Review in Progress [ 10301 ] Ready for Pull Request [ 10304 ]
          bbendick Brandon Bendickson made changes -
          Status Ready for Pull Request [ 10304 ] Pull Request Submitted [ 10101 ]
          bbendick Brandon Bendickson made changes -
          Status Pull Request Submitted [ 10101 ] Reviewing Pull Request [ 10303 ]
          bbendick Brandon Bendickson made changes -
          Status Reviewing Pull Request [ 10303 ] Merged Needs Testing [ 10002 ]
          bbendick Brandon Bendickson made changes -
          Status Merged Needs Testing [ 10002 ] Post-merge Testing In Progress [ 10003 ]
          bbendick Brandon Bendickson made changes -
          Resolution Done [ 10000 ]
          Status Post-merge Testing In Progress [ 10003 ] Closed [ 6 ]
          robofjoy Robert Reid made changes -
          Resolution Done [ 10000 ]
          Status Closed [ 6 ] To-Do [ 10305 ]
          robofjoy Robert Reid made changes -
          Status To-Do [ 10305 ] In Progress [ 3 ]
          robofjoy Robert Reid made changes -
          Assignee Robert Reid [ robertreid ] Brandon Bendickson [ bbendick ]
          ann.loraine Ann Loraine made changes -
          Sprint Fall 1, Fall 2 [ 83, 225 ] Fall 1, Fall 2, Fall 3 [ 83, 225, 226 ]
          ann.loraine Ann Loraine made changes -
          Rank Ranked higher
          bbendick Brandon Bendickson made changes -
          Status In Progress [ 3 ] Needs 1st Level Review [ 10005 ]
          bbendick Brandon Bendickson made changes -
          Status Needs 1st Level Review [ 10005 ] First Level Review in Progress [ 10301 ]
          bbendick Brandon Bendickson made changes -
          Status First Level Review in Progress [ 10301 ] Ready for Pull Request [ 10304 ]
          bbendick Brandon Bendickson made changes -
          Status Ready for Pull Request [ 10304 ] Pull Request Submitted [ 10101 ]
          bbendick Brandon Bendickson made changes -
          Status Pull Request Submitted [ 10101 ] Reviewing Pull Request [ 10303 ]
          bbendick Brandon Bendickson made changes -
          Status Reviewing Pull Request [ 10303 ] Merged Needs Testing [ 10002 ]
          bbendick Brandon Bendickson made changes -
          Status Merged Needs Testing [ 10002 ] Post-merge Testing In Progress [ 10003 ]
          bbendick Brandon Bendickson made changes -
          Resolution Done [ 10000 ]
          Status Post-merge Testing In Progress [ 10003 ] Closed [ 6 ]

            People

            • Assignee:
              bbendick Brandon Bendickson
              Reporter:
              robofjoy Robert Reid
            • Votes:
              0 Vote for this issue
              Watchers:
              2 Start watching this issue

              Dates

              • Created:
                Updated:
                Resolved: