Please also look to see if APIs are available from services such as dbSNP.

The above service is in Beta Testing stage and the website advises that we should restrict the request to 1 request per second (as of now). It can fetch important information that can be helpful for the end user.
To solve this problem we can lazy load data as the user browses the genome. We will also need to look at how we visualize the data if we intend to use this service.

http://www.hgmd.cf.ac.uk/ac/index.php

I have attached the list of links that SNPeida has on their website if that is what we are looking at.

This could be very useful for showing summary information about variants:
https://myvariant.info/
It is a REST service that returns JSON with summary information about SNPs and other variants.
The Web site above has examples showing how to use it.
It is one of the "biothings" APIs which brings together a lot of information about genomic entities into computer-friendly formats.
So for example, IGB could use the information directly, or IGB could link to a Web page (hosted on Bioviz or some other site) that shows data from the REST service. There are a lot of possibilities.
Attached is a sample output in json - the same example from the Web site, which is: https://myvariant.info/v1/variant/chr6%3Ag.152708291G%3EA?dotfield=true&callback=%20