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  1. IGB
  2. IGBF-900

IPS search may fail for some gene models

    Details

    • Type: Bug
    • Status: Closed (View Workflow)
    • Priority: Major
    • Resolution: Done
    • Affects Version/s: None
    • Fix Version/s: None
    • Labels:
      None

      Description

      While testing I noticed that the IPS Search may fail for some gene models such as this one from the Bos Taurus genome, Chr1: NM_174504

      After taking a look at this further it seems that this is failing when running through IPS without using IGB.

      This may be because these gene models contain several stop codons in their protein sequence. (See screenshot).

      We should examine why these gene models contain these stop codons.

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            mason Mason Meyer (Inactive) created issue -
            mason Mason Meyer (Inactive) made changes -
            Field Original Value New Value
            Epic Link IGBF-439 [ 15497 ]
            mason Mason Meyer (Inactive) made changes -
            Rank Ranked higher
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            mason Mason Meyer (Inactive) added a comment -

            I think that a failure occurs for any protein sequences that contains more than one stop codon and for gene models that do not have a CDS start or end.

            Show
            mason Mason Meyer (Inactive) added a comment - I think that a failure occurs for any protein sequences that contains more than one stop codon and for gene models that do not have a CDS start or end.
            dcnorris David Norris (Inactive) made changes -
            Rank Ranked lower
            dcnorris David Norris (Inactive) made changes -
            Rank Ranked higher
            dcnorris David Norris (Inactive) made changes -
            Sprint Backlog Grooming Meeting [ 34 ] Backlog Grooming Meeting 2 [ 35 ]
            mason Mason Meyer (Inactive) made changes -
            Link This issue relates to IGBF-906 [ IGBF-906 ]
            mason Mason Meyer (Inactive) made changes -
            Link This issue relates to IGBF-907 [ IGBF-907 ]
            Hide
            mason Mason Meyer (Inactive) added a comment -

            This story has been separated into 2 stories: IGBF-906 and IGBF-907.

            Since this story is no longer needed it will now be closed.

            Show
            mason Mason Meyer (Inactive) added a comment - This story has been separated into 2 stories: IGBF-906 and IGBF-907 . Since this story is no longer needed it will now be closed.
            mason Mason Meyer (Inactive) made changes -
            Assignee Mason Meyer [ mason ]
            mason Mason Meyer (Inactive) made changes -
            Resolution Done [ 10000 ]
            Status Open [ 1 ] Closed [ 6 ]
            ann.loraine Ann Loraine made changes -
            Workflow Loraine Lab Workflow [ 16310 ] Fall 2019 Workflow Update [ 19632 ]
            ann.loraine Ann Loraine made changes -
            Workflow Fall 2019 Workflow Update [ 19632 ] Revised Fall 2019 Workflow Update [ 21751 ]

              People

              • Assignee:
                mason Mason Meyer (Inactive)
                Reporter:
                mason Mason Meyer (Inactive)
              • Votes:
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                Dates

                • Created:
                  Updated:
                  Resolved: