Does this happen with release 9.0.0 ?

yes, it happens with 9.0.0 as well.

Is this still a problem?
For the next step in addressing this, please attempt to reproduce the problem. If it is possible, please create a video recording demonstrating the parts of the UI that are "zoomed" ( as noted by Kiran Korey).

[~aloraine] This issue seems to be not present anymore. I am using a 27 inch, 4K monitor to test this.
When launching IGB with "High DPI scaling override" activated, IGB launches in a larger size window compared to before, however the UI is not over up-scaled, and no issues were visible.

Screenshot before enabling up-scaling: https://i.imgur.com/chUmP8f.jpg
Screenshot after enabling up-scaling: https://i.imgur.com/eJalXQb.jpg

Moving this ticket to "Needs 1st Level Review".

Jay Chamma, is there something we can change in IGB so that "High DPI scaling override" is automatically enabled by default in Windows? That way the user doesn't have to do anything?

If there is no way to automatically set the "High DPI scaling override", then we should add a page to the IGB User's Guide (for example under Troubleshooting) on how to fix scaling of IGB on Windows for High DPI (>=4K) screens. Would need to include new images with callouts conforming to the IGB User's Guide and steps to solve the issue.

Nowlan Freese, according to the following link, it is possible to enable this feature on IGB by default.
https://blogs.windows.com/windowsdeveloper/2017/05/19/improving-high-dpi-experience-gdi-based-desktop-apps/
It goes into detail about topics of which I am inexperienced in, so I cannot make a full judgement regarding how difficult it is to add this feature to IGB, but it is definitely possible to do so.

Image 1.png shows an option "Edit with Notepad++". Is this a plain text file that can be edited? If yes, I would like to see the contents following data anonymization (no computer- or user-specific details visible.)

[~aloraine], the file is editable and most of the text inside it is gibberish: https://i.imgur.com/vSIfMyb.png
I found 2 sections with plain English text:
https://i.imgur.com/oo5hteg.png
and
https://i.imgur.com/18wQDYi.png

After speaking with Nowlan Freese, I tested this possible issue on both v9.1.4 from BioViz and v9.1.6 (master.exe) and this is what I found:

• After enabling the "High DPI scaling override" option on both v9.1.4 and v9.1.6, no oversize font issues were present.
• I also tested this after exporting a bookmark (as per instructions of the ticket description) to see if that causes the issue, but that didn't cause any font issues.
• Additionally, I separately checked to see if the the Windows Scale and Layout options that is used to scale up font and apps for high DPI displays was causing this issue, which has options to scale apps between (100% - 350%). However, this setting also did not cause any font issues upon launching both versions of IGB.
  The monitor I used to test this is a 27" 4K monitor.

I am closing this ticket as the text scaling problem is not reproducible or no longer an issue when overriding high DPI scaling on Windows.

I have created a new issue (IGBF-2503) to create a new page describing how to override the high DPI scaling settings on Windows.